Project: PERSONMED – Center for the Development of Personalized Medicine in Age-Related Diseases
Registration number: CZ.02.1.01/0.0/0.0/17_048/0007441
Funded by: Ministry of Education, Youth and Sports, OP Research, Development and Education
Programme
1st European workshop on intra-amniotic infection/inflammation
9:15 – 9:30
I. Opening of the workshop – welcome
Prof. Vladimir Palicka, M.D., Ph.D., Dr.h.c., (Hradec Kralove, Czech Republic)
Director, University Hospital Hradec Kralove
Prof. Jiri Mandak, M.D, Ph.D., (Hradec Kralove, Czech Republic)
Dean, Charles University, Faculty of Medicine in Hradec Kralove
Prof. Jiri Spacek, M.D., Ph.D., (Hradec Kralove, Czech Republic)
Head, Department of Obstetrics and Gynecology, University Hospital Hradec Kralove
Bc. Pavel Bulíček (Hradec Kralove, Czech Republic)
First deputy Governor of the Hradec Kralove region
9:30 – 11:10
II. Preterm delivery and intra-amniotic inflammation
Prof. Jan Krejsek, Ph.D. (Hradec Kralove, Czech Republic)
Inflammation – an immunologist point of view (20 min)
Prof. Bo Jacobsson, M.D., Ph.D. (Gothenburg, Sweden)
Preterm birth – a global perspective (20 min)
Prof. Teresa Cobo, M.D., Ph.D. (Barcelona, Spain)
Spontaneous preterm labor and intra-amniotic inflammation (20 min)
Prof. Marian Kacerovsky, M.D., Ph.D. (Hradec Kralove, Czech Republic)
Preterm prelabor rupture of membranes and intra-amniotic inflammation (20 min)
Discussion (20 min)
11:10 – 11:30
Coffee break
11:30 – 12:20
II. Animal models and intra-amniotic inflammation
Prof. Ramkumar Menon, Ph.D. (Galvestone, US)
Development of a mouse model of ascending infection and preterm birth (20 min)
Ass. Prof. Ivana Musilova, M.D., Ph.D. (Hradec Kralove, Czech Republic)
Development of a rat model of intra-amniotic inflammation via ultrasound-guided administration of a trigerring agent (20 min)
Discussion (10 min)
12:20 – 13:20
Lunch
13:20 – 14:20
III. Cervical/vaginal microbiota and intra-amniotic inflammation
Prof. Ronald Lamont, M.D., Ph.D. (London, UK)
Vaginal microbiome and preterm birth (20 min)
Prof. Ramkumar Menon, Ph.D. (Galvestone, US)
Cervical infection and inflammation in preterm birth (20 min)
Prof. Marian Kacerovsky, M.D, Ph.D. (Hradec Kralove, Czechia)
Cervical microbiome and intra-amniotic inflammation in preterm prelabor rupture of membranes (10 minutes)
Discussion (10 minutes)
14:20 – 14:40
Coffee break
14:40 – 17:10
IV. Intra-amniotic inflammation – how to …
Prof. Vedran Stefanovic, M.D., Ph.D. (Helsinki, Finland)
How to assess intra-amniotic inflammation in amniotic fluid (20 min)
Rudolf Kukla, Ph.D. (Hradec Kralove, Czech Republic)
How to identify of microorganisms and/or their nucleic acids in amniotic fluid. (20 min)
Marie Vajrychová Ph.D. (Hradec Kralove, Czech Republic)
How to perform proteomic analysis of amniotic fluid with respect to intra-amniotic inflammation (20 min)
Ass. Prof. Ivana Musilova, M.D., Ph.D. (Hradec Kralove, Czech Republic)
How to use an ultrasound to predict the risk of intra-amniotic inflammation (20 min)
Jaroslav Stranik, M.D., Ph.D. (Hradec Kralove, Czech Republic)
How to invasively and non-invasively obtain a sample of body fluid to assess intra-amniotic environment (20 min)
Prof. Teresa Cobo M.D., Ph.D. (Barcelona, Spain)
How to non-invasively predict intra-amniotic infection and early delivery in preterm labor with intact membranes (20 min)
Prof. Marian Kacerovsky M.D., Ph.D. (Hradec Kralove, Czech Republic)
How to treat intra-amniotic inflammation (10 min)
Discussion (20 min)
17:10 – 17:30
Coffee break
17:30 – 18:30
V. Intra-amniotic inflammation and neonatal outcomes
Clara Murillo, M.D., Ph.D.c. (Barcelona, Spain)
Fetal cardiovascular impact of subclinical intra-amniotic infection/inflammation (20 min)
Jana Zemankova M.D., Ph.D. (Hradec Kralove, Czech Republic)
Intra-amniotic inflammation and long-term neonatal outcomes (10 min)
Jana Matulova, MSc., Ph.D.c (Hradec Kralove, Czech Republic)
Intra-amniotic inflammation and birthweight (10 min)
Discussion (20 min)
18:30
VI. Closing of the workshop